CHICKEN POX

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Chicken pox ,also called varicella ,is a highly contagious disease caused by the varicella - zooster virus .This virus is a member of the herpes virus family ,and humans are…

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DIABETES

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Diabetes is a chronic disease that occurs either when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces . Insulin is…

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SOUTH SUDAN-PIC
[A make-shift cholera treatment centre in South Sudan. Photo/courtesy/CARE/February, 27, 2025].

South Sudan faces deadly cholera outbreak, funding shortfalls threaten response

JUBA, SOUTH SUDAN – 27 FEB 2025 –South Sudan is facing an alarming cholera outbreak, with over 26,800 infections and 455 deaths across 39 counties in eight states. The crisis…

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GONORRHOEA

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Gonorrhoea is a preventable and curable sexually transmitted infection caused by the bacterium (Neisseria gonorrhoea),which is primarily transmitted through vaginal,oral or anal sex.Gonorrhoea is a common sexually transmitted infection caused…

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SYPHILIS

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Syphilis is a preventable and curable bacterial sexually transmitted infection (STI).If untreated,it can cause serious health issues .Many people with syphilis do not have symptoms or do not notice them.…

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HYPERTENSION

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Hypertension (high blood pressure)is when the pressure in yiur blood vessel is too high (140/90mmhg or higher).It is common but can be serious if not treated . People with high…

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HEALTHY DIET

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A healthy diet helps to protect against malnutrition in all it's forms,as well as non-communicable diseases (NCDs) including diabetes ,heart disease,stroke and cancer. Unhealthy diet and lack of physical activity…

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Dr Oriol Dols and Esther Álvarez-Sánchez, researchers in the Neurobiology of Dementias group and Memory Unit at IR Sant Pau

IR Sant Pau study reveals immune system’s crucial role in ALS at cellular level

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of Neuroinflammation that, for the first time, examines in depth…

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This new platform integrates computational design and directed evolution to develop new antibodies, which are screened for their ability to bind to toxic aggregates that form in diseases like Parkinson's and Alzheimer's.

Designing antivirals for shape-shifting viruses

Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication. However, viruses are…

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This new platform integrates computational design and directed evolution to develop new antibodies, which are screened for their ability to bind to toxic aggregates that form in diseases like Parkinson's and Alzheimer's.

New antibody discovery platform can inform Alzheimer’s and Parkinson’s

In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping is called protein aggregation and…

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Fial
Illustration of the mechanics of interface flexibility in DNA networks © PBL EPFL

Scientists discover mechanism driving molecular network formation

Covalent bonding is a widely understood phenomenon that joins the atoms of a molecule by a shared electron pair. But in nature, patterns of molecules can also be connected through…

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Low-Res_Menthol Cigarettes
New ACS Study Finds Menthol Flavored Cigarette Smoking Increases Mortality Risk vs. Non-Menthol Cigarettes

New ACS study finds menthol flavored cigarette smoking increases mortality risk vs. non-menthol cigarettes

In a large, nationwide study led by the American Cancer Society (ACS), researchers found mortality risks for smoking menthol cigarettes were higher than non-menthol cigarettes for death from any cause…

Continue ReadingNew ACS study finds menthol flavored cigarette smoking increases mortality risk vs. non-menthol cigarettes

Research suggests comprehensive CT scans may help identify atherosclerosis among lung cancer patients

Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart…

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New study adds to evidence of stroke and heart attack risk with some hormonal contraceptives

Certain hormonal contraceptives are associated with a higher stroke and heart attack risk, finds a large study from Denmark in The BMJ today that draws on prescription records to give more precise…

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lung
Study shows lung cancer patients are at increased risk for cardiovascular disease and comprehensive assessments could improve survival outcomes

Lung cancer cells can go ‘off grid’

Researchers from the Francis Crick Institute have found that some particularly aggressive lung cancer cells can develop their own electric network, like that seen in the body’s nervous system. This…

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brain
UCLA Health researchers say these signals can serve as critical biomarker to detect patients with high seizure risk

New perspectives for personalized therapy of brain tumors

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original…

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A diabetes, heart failure, and kidney disease medication is the first of its kind to significantly reduce both heart attacks and strokes

Sotagliflozin, a drug recently approved by the Food and Drug Administration to treat type 2 diabetes and kidney disease with additional cardiovascular risk factors, can significantly reduce heart attack and…

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brain
UCLA Health researchers say these signals can serve as critical biomarker to detect patients with high seizure risk

New perspectives for personalized therapy of brain tumors

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original…

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brain
UCLA Health researchers say these signals can serve as critical biomarker to detect patients with high seizure risk

Brain rhythms can predict seizure risk of Alzheimer’s disease patients, study finds

A UCLA Health research team has identified changes in brain rhythms that indicate seizure activity in Alzheimer’s patients.   The findings, published in Brain Communications, build on UCLA neurologist and senior…

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Jared Fischer, Ph.D., and Jose Luis Montoya Mira, Ph.D., cancer researchers at Oregon Health & Science University, have developed PAC-MANN, a test that uses a small blood sample to detect changes in protease activity, a key indicator of pancreatic ductal adenocarcinoma (PDAC), the most common and deadliest form of pancreatic cancer. (OHSU/Christine Torres Hicks)

New blood test identifies hard-to-detect pancreatic cancer with 85% accuracy

A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers. Researchers at Oregon Health & Science University have developed…

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Targeting cardiomyocyte steatosis cures heart failure:

A simple supplement improves survival in patients with a new type of heart disease

Heart transplant is a scary and serious surgery with high cost, but for patients with heart failure it can be the only option for cure. Now, however, a multi-institutional research…

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smo
New ACS Study Finds Menthol Flavored Cigarette Smoking Increases Mortality Risk vs. Non-Menthol Cigarettes

New ACS study finds menthol flavored cigarette smoking increases mortality risk vs. non-menthol cigarettes

In a large, nationwide study led by the American Cancer Society (ACS), researchers found mortality risks for smoking menthol cigarettes were higher than non-menthol cigarettes for death from any cause…

Continue ReadingNew ACS study finds menthol flavored cigarette smoking increases mortality risk vs. non-menthol cigarettes
lung
Study shows lung cancer patients are at increased risk for cardiovascular disease and comprehensive assessments could improve survival outcomes

Research suggests comprehensive CT scans may help identify atherosclerosis among lung cancer patients

Several cardiovascular risk factors, such as advanced age and smoking history, are prevalent among lung cancer patients at the time of the diagnosis and increase their risk of future heart…

Continue ReadingResearch suggests comprehensive CT scans may help identify atherosclerosis among lung cancer patients
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Jane Lombard, MD, medical director of the Women’s Heart Center at El Camino Health

Survey: Women prefer female doctors, but finding one for heart health can be difficult

yAccording to the U.S. Physician Workforce Data Dashboard, only about 17% of cardiologists are women, ranking as one of the lowest specialties among female physicians, yet heart disease remains the…

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GG
It’s been theorized that ketamine works by blocking a brain receptor called GluN1-2B-2D. Here, we see one of the many ways the drug’s chemical molecules (yellow) can bind to a specific part (the gray web) of the brain receptor.

Ketamine: From club drug to antidepressant?

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed…

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It’s been theorized that ketamine works by blocking a brain receptor called GluN1-2B-2D. Here, we see one of the many ways the drug’s chemical molecules (yellow) can bind to a specific part (the gray web) of the brain receptor.

Ketamine: From club drug to antidepressant?

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed…

Continue ReadingKetamine: From club drug to antidepressant?
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UBC associate professor of cellular and physiological sciences Dr. Mark Cembrowski (left) and PhD student Adrienne Kinman observe ovoid cells active in the hippocampus of a mouse.

Meet the newly discovered brain cell that allows you to remember objects

Take a look around your home and you’ll find yourself surrounded by familiar comforts—photos of family and friends on the wall, well-worn sneakers by the door, a shelf adorned with…

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Prioritise vaccine boosters for vulnerable immunocompromised patients and prevent emergence of new COVID variants, say scientists

Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University…

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brain
UCLA Health researchers say these signals can serve as critical biomarker to detect patients with high seizure risk

Brain bleeds increase the risk of dementia

Weill Cornell Medicine researchers have found that intracranial hemorrhages, or "brain bleeds" caused by a ruptured blood vessel in the brain, double a person’s risk of developing dementia later in…

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A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma

Immunotherapy against melanoma: efficacy can be predicted with a chip

A team of researchers from the European Institute of Oncology and the Politecnico di Milano, coordinated by Luigi Nezi, Team Leader of the Department of Experimental Oncology, European Institute of…

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Stalled microbiomes: Dartmouth-led study reveals that cystic fibrosis disrupts early gut development in infants

Stalled Microbiomes: Dartmouth-led Study Reveals That Cystic Fibrosis Disrupts Early Gut Development in Infants   Findings from a new Dartmouth-led study, published in the journal mBio, highlight key differences in the gut…

Continue ReadingStalled microbiomes: Dartmouth-led study reveals that cystic fibrosis disrupts early gut development in infants

Research shows blood test may provide personalized dietary therapy for patients with irritable bowel syndrome

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the…

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dog
Suzie, cider and student: Susie and her dog Cider who have been long-term Palouse Paws handlers.

Regular access to therapy dogs boosts first-year students’ mental health

College students who spent a little bit of free time each week interacting with therapy dogs on campus during their first semester experienced fewer signs of stress and depression than…

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BAT
New research has revealed evidence suggesting British American Tobacco Kenya (BATK) may have avoided or evaded up to $28 million in profit taxes in Kenya

New report reveals potential $28 million tax discrepancy involving British American Tobacco in Kenya

New research has revealed evidence suggesting British American Tobacco Kenya (BATK) may have avoided or evaded up to $28 million in profit taxes in Kenya. The analysis, written by The…

Continue ReadingNew report reveals potential $28 million tax discrepancy involving British American Tobacco in Kenya
Franzos
Quasar Padiath, M.B.B.S., Ph.D., professor and chair of the University of Pittsburgh School of Public Health Department of Human Genetics

Gene ‘silencer’ in junk DNA prevents fatal neurological disease

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene “silencer” that resides in junk DNA is directly sparing…

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Insights from an international team include identification of beneficial bacteria that thwart disease

Disordered eating and certain foods linked to higher risk for urinary incontinence in middle-aged women

According to a recent study conducted at the University of Jyväskylä, eating behaviour is associated with symptoms of pelvic floor disorders in middle-aged women. For example, higher consumption of highly…

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James Antoon, MD, PhD, MPH, assistant professor of Pediatrics at Monroe Carell Jr. Children’s Hospital at Vanderbilt

Neurologic complications of flu nearly 50 times greater for children with underlying neurologic conditions

Many clinicians do not consider neurologic complications of the flu when discussing vaccination or treatment of influenza with families.   A recent study that explored the neurologic impact of flu…

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ToveSmeds
Experimental scientist Ilknur Özen and clinical scientist Niklas Marklund, professor at Lund University and neurosurgical consultant at Skåne University hospital.

Cracking the Alzheimer’s code: how brain trauma triggers disease

An increased risk of dementia among individuals exposed to brain trauma, traumatic brain injury, has been known for almost a century. Still, we know very little about the molecular causes…

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Innovative dual-target drug may lead to new investigational approach for breast cancer patients

Researchers, led by the University of Melbourne’s Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at the Peter Doherty Institute of Infection and Immunity (Doherty Institute), in collaboration…

Continue ReadingInnovative dual-target drug may lead to new investigational approach for breast cancer patients
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Loneliness and social isolation were associated with an elevated risk of NAFLD, independent of other important risk factors.

Loneliness and social isolation linked to increased risk of non-alcoholic fatty liver disease, study finds

Loneliness and social isolation have been linked to an elevated risk of non-alcoholic fatty liver disease (NAFLD), according to a groundbreaking study conducted by researchers from Central South University and…

Continue ReadingLoneliness and social isolation linked to increased risk of non-alcoholic fatty liver disease, study finds
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(a) Effector Tregs (eTregs) most strongly affect CD8-EM cells and B-plasma cells. (b) A closer look reveals eTregs control CD8-EM cells by stopping their division and reducing GzmB while maintaining CD27. (c) Dividing eTregs increase CD98, GLUT1, and CTLA4 proteins, and shows how an anti-CTLA4 antibody affects this process. (d) Reveals a potential biomarker by showing two distinct types of eTregs: one expressing HLA-DR and CCR4, and another expressing CD38 and CCR7 - a pattern seen in severe viral infections. (e) Ranks different Treg types by their suppressive ability, with eTregs being strongest. (f) Demonstrates how the drug Tazemetostat blocks naive Tregs from becoming eTregs during early cell division.

New immune-probing technique could boost treatment discovery

Developing effective treatments and understanding how the mechanism of the immune system have always been challenging for scientists. T cells, which are the frontline warriors in the battle against the…

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Extensive study on telemedicine for diabetes and coronary heart disease – Senior author concludes: “The hype around medical apps needs to be put into perspective”

Can telemedicine and exercise apps improve the health of people with type 2 diabetes and coronary heart disease? A large study led by the Technical University of Munich (TUM) shows…

Continue ReadingExtensive study on telemedicine for diabetes and coronary heart disease – Senior author concludes: “The hype around medical apps needs to be put into perspective”
CONDOM-PIC-compressed
[Youth spreading the AHF International Condoms Day message in the streets of Mathare in Kenya’s Capital, Nairobi on Feb’ 13, 25].

AHF calls for condom access reforms amid rising costs, unavailability

Despite over 1 million Sexually Transmitted Infections (STIs) being acquired globally each day, condom access in Kenya remains a pressing challenge, exacerbated by dwindling donor funding and high taxation on…

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A new large-scale, global survey has revealed that most people want harmful social media content such as physical threats and defamation to be restricted

Majority support moderation on social media platforms, global survey shows

The global debate on whether and how social media content should be regulated has flared up again in recent months. Citing freedom of expression, the platform operators X and Meta…

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Randomized, placebo-controlled trial confirms side effect seen by many doctors and patients

Ozempic shows promise in reducing cravings for alcohol, heavy drinking

The blockbuster drug semaglutide, better known as Ozempic for diabetes and Wegovy for obesity, could also help people cut down on their alcohol intake, according to new USC research. The…

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A new study shows that gut bacteria can influence the molecular pattern of glycosylation – the presence of sugar groups on proteins – in the brain.

Bacteria, brains, and sugar: scientists uncover new connections

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease. A…

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Corrosion-Induced CoCuMW/CF electrode for electroreduction of HMF to BHMF.

Scientists develop corrosion-induced electrodes for biomass upgrading

A research team led by Prof. ZHANG Jian from the Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS) has utilized metal corrosion to…

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Researchers investigated the links between depression and physical health conditions.

Depression linked with higher risk of long-term physical health conditions

Adults with a history of depression gain long-term physical conditions around 30% faster than those without, according to research publishing February 13th in the open-access journal PLOS Medicine. Kelly Fleetwood…

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Guardian molecule keeps cells on track – new perspectives for the treatment of liver cancer

A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational…

Continue ReadingGuardian molecule keeps cells on track – new perspectives for the treatment of liver cancer
trac
Insights from an international team include identification of beneficial bacteria that thwart disease

Ovarian cancer discovery could turn failed treatment into lifesaver

University of Virginia Cancer Center researchers have explained the failure of immune checkpoint therapy for ovarian cancer by discovering how gut bacteria interfere with the treatment. Doctors may be able…

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Tumors can drive thrombosis by releasing chemokines, secreted proteins that can circulate to the lung. This image of a lung sample shows how immune cells called macrophages release small vesicles (green) that attach to platelets (magenta), which can form life-threatening blood clots. Cell nuclei are shown in blue.

A single-dose breakthrough: PfSPZ-LARC vaccines offer transformative protection against malaria

Scientists at Sanaria and Seattle Children’s Research Institute’s Center for Global Infectious Disease Research (CGIDR) have unveiled a groundbreaking malaria vaccine, Sanaria® PfSPZ-LARC2 Vaccine, designed to provide high-level protection with…

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A new study shows that postnatal exposure to tobacco smoke alters DNA methylation, which may help explain adverse health effects

How the DNA’s environment shapes smoking-related cancer risk

The study from The Hebrew University of Jerusalem, led by Prof. Sheera Adar and her graduate student Elisheva Heilbrun-Katz from The Institute for Medical Research Israel-Canada in the Faculty of…

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